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Centre-specific estimates were pooled using a fixed effects meta-analysis. Results There was no difference in patient-reported outcome measures between the routine care and intensive treatment arms in this 10-year follow-up study [EQ-5D -0.01 (95% CI -0.03, 0.01); Physical Composite Score (36-item Short-Form Health Survey) -0.27 (95% CI -1.11, 0.57), Audit of Diabetes-Dependent Quality of Life questionnaire -0.01 (95% CI -0.11, 0.1; and Diabetes Treatment Satisfaction Questionnaire -0.20 (95% CI -0.70, 0.29)]. Conclusions Intensive, multifactorial treatme