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For patients with temporal neocortical onset, the most prevalent IOP pattern was LVFA with a mean discharge rate 35Hz, followed by runs of spikes. Compared with Lateral TLE (LTLE), the duration between the onset of the IOPs to the onset of the symptom was longer for patients with MTLE (Mesial TLE) (MTLE55.7 ± 50.6s vs LTLE19.5 ± 16.4s). Multiple IOPs underlie seizure generation in patients with TLE. However, the mesial and lateral temporal lobes share distinct IOPs. Multiple IOPs underlie seizure generation in patients with TLE. However, the mesial

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