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The objective of this research was to examine if the DDI clearance values from grownups could be allometrically extrapolated from adults to young ones. TECHNIQUES Fifteen drugs had been most notable study in addition to age of the children ranged from early neonates to adolescents (30 observations across the age brackets). The age-dependent exponent (ADE) model ended up being used to predict the approval of drugs in kids from adults after DDI studies. OUTCOMES The forecast mistake
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