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029). Catheter-related thrombosis was observed in PICC  0.5 and CICC  0.6, and occlusion due to blood flow reversal was observed in PICC  0.5 and CICC  0.6. Conclusion  PICCs are safer and more effective than CICCs for the treatment of esophageal cancer, and reduce the incidence of CRBSI. We hope to standardize the insertion procedures, conventionalize techniques, and establish training systems. J. Med. Invest. 67 298-303, August, 2020.As the expression level of allergic disease sensitive genes are correlated with the severity of alle