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AScW can perform maximum improvements of speckle signal-to-noise proportion (sSNR) by 36.4% (simulation) and 44.8% (experiment) weighed against GCF, while 14.4per cent (simulation) and 12.5per cent (experiment) weighed against the scaled Wiener postfilter (ScW). Together with maximal horizontal full width at one half optimum (FWHM) improvements are 51.9% upon GCF and 53.7% upon ScW. Meanwhile, the contrast of AScW is comparable to compared to GCF. Through the outcomes of in-vivo study, AS

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