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Clinical cases have actually explained the formation of injectable amyloidosis with your insulin analogues, however their amyloid core parts of fibrils had been unidentified. To reveal these regions, we have analysed the hydrolyzates of insulin fibrils and its analogues making use of high-performance fluid chromatography and mass spectrometry techniques and found that insulin and its particular analogues have almost identical amyloid core areas that intersect with the predicted amyloid

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