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A role for DNA hypomethylation has recently been suggested in the interaction between bacteria and plants, it is unclear whether this phenomenon reflects a conserved response. Treatment of plants of monocot rice and dicot tomato with nematode-associated molecular patterns (NAMPs) from different nematode species or bacterial PAMP flg22 revealed global DNA hypomethylation. A similar hypomethylation response was observed during early gall induction by Meloidogyne graminicola (Mg) in rice. Evidence for the causal impact of hypomethylation on
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