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Spherical nanoparticles of CEL (CEL-NP) were also prepared using a solvent shifting strategy and evaluated for broad-spectrum sunscreens. A moisturizing cream mixed with CEL-NP exhibited greater sun defense aspect (SPF) and UVA PF (security element) values than that with CEL. In inclusion, CEL-NP had synergistic impacts when combined with a natural UV-filter sunscreen CEL-NP enhanced the SPF and UVA PF values of this sunscreen considerably. Nevertheless, there was clearly no synergistic effect between CEL-
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