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If the price were adjusted under the three thresholds, the payment for pertuzumab would be increased by between 32% and 93%. The proposed MVBR model would provide a stronger economic incentive to develop add-on drugs. The proposed MVBR model would provide a stronger economic incentive to develop add-on drugs. Compartmental models simplify the mathematical modeling of infectious diseases based on reported cases. In the absence of precautions, personal protective equipment, quarantine and social distancing, a Susceptible-Exposed-Infectious

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