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Health effects of long-term exposure to ambient PM vary with regions, and 75% of the deaths attributable to PM were estimated in Asia-Pacific in 2017. This systematic review aims to summarize the existing evidence from cohort studies on health effects of long-term exposure to ambient PM in Asia-Pacific. In Asia-Pacific, 60 cohort studies were conducted in Australia, Mainland China, Hong Kong, Taiwan, and South Korea. They consistently supported associations of long-term exposure to PM with increased all-cause/non-accidental and cardiovas