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We also present a model of cilium emergence during evolution, and summarize the directions for future research.Carcinoma diagnosis and prognosis are still hindered by the lack of effective prediction model and integration methodology. We proposed a novel feature selection with orthogonal regression (FSOR) method to resolve predictor selection and performance optimization. Functional enrichment and clinical outcome analyses with multi-omics information validated the method's robustness in the early-stage prognosis of lung adenocarcinoma. Furthermore, compare
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