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CD44 specific HA-modified carbon dioxide spots (HA-CDs) had been produced since service provider simply by one-step hydrothermal treatment method within one hour along with citric acid and branch-PEI as key as well as source. Haya not simply functioned because co2 department of transportation component but in addition while hydrophilic party and also targeting ligand of this program. The as-prepared HA-CDs have been and then packed with doxorubicin (HA-CD@p-CBA-DOX) through an acid-cleavable connect, which in turn unveiled drug within a pH-responsive

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