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However, top end combined intake may cause a multifold exceedance regarding the ADI of nitrites for individuals with both high and normal transformation capacity.Approximately 2 million endoprostheses are implanted yearly and steel ions along with particles tend to be circulated in to the human body from the materials which are utilized. This review describes the results of researches regarding genotoxic harm due to synthetic joints. DNA harm contributes to numerous unpleasant long-lasting health

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