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Overall, most duels were conducted from the anterior direction. Playing forms induce higher cardio-circulatory load as well as a better learning environment. Potentially dangerous situations like contact with other players or headers occurred in a single player on average every six min during a training session.Primary mitochondrial diseases (PMD) refer to a group of severe, often inherited genetic conditions due to mutations in the mitochondrial genome or in the nuclear genes encoding for proteins involved in oxidative phosphorylation