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Metabolomics analysis showed that acute ozone exposure led to alterations in stress hormones, systemic inflammation, oxidative stress, and energy metabolism. Our results suggest that acute ozone exposure may trigger ANS imbalance and activate the HPA and SAM axes, offering potential biological explanations for the adverse cardiometabolic effects following acute ozone exposure.Citric acid (CA) is the major exudate of rice roots, yet the effects of CA on arsenic (As) transformation and microbial community in flooded paddy soi