What Causes Trucking Accidents? Trucks make up a small portion of the vehicles that travel on the roads but they can cause serious injuries or even death. Accidents involving large trucks can result when drivers are distracted or do not pay attention to their blind spots. Trucking accidents can also be the result of driver fatigue. These drivers often work long hours without rest breaks to meet their quotas. Driver Error Driver error is the number one cause of trucking accidents, and it is a very serious problem. Driver errors can be caused b