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Despite large series divergence, and refined differences in the models, E2 from various strains act similarly, having a stable core flanked by very flexible areas, a few of which perform important features such as for instance receptor binding. Comparison with series information claim that this constant behaviour is conferred by a network of conserved deposits that behave as hinge and anchor things throughout E2. The adjustable regions (HVR-1, HVR-2 and VR-3) exhibit particularly large flexibil
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