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This review focuses on the current state of knowledge and future perspective of novel biomarkers of AKI in cirrhosis.Proper diagnosis is the key to successful management of headache disorders. Separating secondary causes from primary headache disorders is a necessary first step, followed by further refinement within these broader categories. For research into the physiological and pathophysiological underpinnings of headache disorders, distinguishing headache types and subtypes is even more crucial. Thus, classification of headache type