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011), sleep duration and 10-year ASCVD risk ( -trend 0.001), as well as sleep duration and CRP ( -trend 0.001). A self-reported sleep duration of 6-7 hours appeared most optimal. We observed that those participants who reported 6 or 7 hours of sleep had higher risk of CV death attributable to inflammation after accounting for confounders. There was a U-shaped relationship of incident CV mortality, 10-year ASCVD risk, and CRP with sleep duration. These findings suggest an interplay between sleep duration, inflammation, and C