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To determine the prevalence of hypocomplementemia in primary Sjogren's syndrome (pSS) patients and compare the clinical characteristics of patients with and without hypocomplementemia. A retrospective study was conducted in 120 treatment-naive Chinese patients that met the 2012 American College of Rheumatology Classification Criteria for pSS and were followed up for 3 to 24 months. Based on the complement results, patients were divided into four groups only low C3, only low C4, both low C3 and C4 (double low), normal group. The data on