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Thus, our data demonstrated that IL-17A and IL-17F are not encephalitogenic mediators but rather modulators of intestinal homeostasis that indirectly alter CNS-directed autoimmunity.Flares of acute itch in the setting of atopic dermatitis may engage a novel neuroimmune axis that includes basophils, LTC4, and sensory neurons.Treg-specific ablation of TGF-β clarifies the complicated role of Treg-derived TGF-β in immunosuppression in vivo.GATA-2-mediated E-cadherin expression marks early progenitors primed to the basophil and mast cell lineag