https://www.selleckchem.com/pr....oducts/l-histidine-m
The new complexes [Zn(ITZ)2Cl2] (1) and [Zn(ITZ)2(OH)2] (2) were synthetized by a reaction of itraconazole with their respective zinc salts under reflux. These Zn-ITZ complexes were characterized by elemental analyses, molar conductivity, mass spectrometry, 1H and 13C1H nuclear magnetic resonance, UV-vis and infrared spectroscopies. The antiparasitic and antifungal activity of Zn-ITZ complexes was evaluated against three protozoans of medical importance, Leishmania amazonensis, Trypanosoma cruzi and Tox