https://www.selleckchem.com/pr....oducts/sb-505124.htm
Moreover, VRK1 might regulate the expression of β-catenin (CTNNB1) at the transcriptional level by phosphorylating c-Jun, the transcriptional factor of β-catenin. VRK1 changes the subcellular location and decreases the nuclear aggregation of c-Jun by phosphorylating the Ser243 site. To conclude, VRK1 can affect migration and invasion by regulating the expression of β-catenin at the transcriptional level in GC cells.AHNAK nucleoprotein 2 (AHNAK2) has been proposed to have an oncogenic role in various human cancers. However, the functio