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https://www.selleckchem.com/pr....oducts/donafenib-sor
According to the KRYSTAL-1 study, the KRASG12c inhibitor adagrasib, also known as MRTX849, is largely well tolerated and shows considerable efficacy in patients with non-small cell lung cancer harboring this mutation. The drug is also active, albeit more modestly, in colorectal cancer and several other solid tumor types.Single mouse testing may be an efficient approach to assess cancer therapies in children. In a prospective study, researchers established that single mouse models provided results similar to conventional t

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