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The final results established that Semen Strychni caused neuronal degeneration inside the hippocampal CA1 region. In the mean time, Sperm Strychni limited the mRNA phrase associated with NMDAR1, NMDAR2A, NMDAR2B, GABRa1, GABRb2 and also reduced the level of MAO, which usually upset the particular Idet and also 5-HT metabolic pathway. However, isoliquiritigenin solved these kinds of effects. To conclude, isoliquiritigenin demonstrated alleviation effects about Ejaculate Strychni-induced neurotoxicity, that may become due to rebuilding ne