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Moreover, we reveal that neutral SMase inhibitors disrupt the PM localization of K-Ras and PtdSer and oncogenic K-Ras signaling. In amount, this study identifies avicin G as a new powerful anti-Ras inhibitor, and shows that neutral SMase could be a tractable target for establishing anti-K-Ras therapeutics.Realizing of full-color quantum-dot Light-emitting Diode show s
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