https://www.selleckchem.com/pr....oducts/valemetostat-
Salvage abdomino-perineal resection was performed in 10 patients, 2 had resections of metastases, and 3 both. DFS was 85% at 3 years and 78% at 5 years. OS was 93% at 3 years and 86% at 5 years. In analyses adjusted for age and gender, HPV negative tumours (HR 2.5, = 0.024), N3 disease (HR 2.6, = 0.024), and tumour size ≥4 cm (HR 2.4, = 0.038) were negative prognostic factors for DFS. State-of-the-art chemoradiotherapy for SCCA resulted in excellent outcomes, and improved survival compared with previous national data, wi