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We report a 16-year old male, acquired HIV infection vertically, had been on second line regimen because of virological failure since 3 years. Their present CD4 lymphocyte matter is 835 cells/uL with viral RNA degree of 33,008 copies/mL. Currently served with progressive forgetfulness, gait instability, and a frequent staring attacks without loss in postural tone. Neurologic examination had been pertinent for cognitive dysfunction with