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The mixed-effects model and the meta-analytic approach are suggested as appropriate to average the parameters across repeated dose-response experiments. © 2021 Society of Chemical Industry. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an essential tool in the diagnosis of pancreatic lesions. The aim of this study was to evaluate the diagnostic accuracy of cytology from EUS-FNA, to correlate the results with the corresponding histopathological diagnoses and to analyse the impact of retrospective assignment of the Papa