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Using the pancolonic UCEIS cutoff value of 3, Kaplan-Meier curve analysis showed that patients with endoscopic activity had a significantly lower relapse-free rate than those with endoscopic remission (P0.01). Multivariate analysis demonstrated endoscopic (pancolonic UCEIS 3) and histological (Geboes 3. activities as independent risks for relapse (HR 3.96 and 3.48, respectively). Combining pancolonic UCEIS ≤3 and Geboes score ≤3.0 to provide 1-year relapse avoidance was 92.0% sensitive and 97.0% specific. Evaluating disease