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By regression evaluation, hypertrophy substrate (HCM vs. hypertension) and hypertrophy magnitude were the variables to influence 2D-3D LS and CS strain correlations (R2 = 0.66, P less then 0.001 and R2 = 0.5, P = 0.001 consequently). Among segmental deformation indices, 2D_LS showed the greatest area underneath the curve [AUC = 0.78, 95% self-confidence intervals (CI) (0.75-0.81), P less then 0.0005] to detect fibrosis, with 3D deformation parameters showing si
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