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The in silico results showed that the Nyquist velocity could be extended up to four times the theoretical limit. In vivo, dealiased CFI were highly consistent with unfolded Spectral Doppler ( r2=0.83 , y=1.1x+0.1 , N=25 ) and provided consistent vector flow images. Our results demonstrate that dual-wavelength processing is an efficient method for high-velocity CFI.Ultrasound Localization Microscopy (ULM) can resolve the microvascular bed down to a few micrometers. To achieve such performance, microbubble contrast agents must perfuse the
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