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Functional proteome tools were applied to comprehensively delineate the worldwide necessary protein modifications that mirror the kinds of biological features involving the two subtypes. In this research, a total of 11 proteins with considerable and significant modifications had been identified. These necessary protein targets including PRX2, CK19, nucleophosmin and cathepsin D were mostly taking part in cellular differentiation or proliferation. Specially, cathepsin D had been very expressed within the lum
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