https://www.selleckchem.com/pr....oducts/cct128930.htm
RESULTS Cluster analysis of the whole genome sequencing revealed that the frequency of chromosomal aberrations were increased in ACC with local recurrence and distant metastases in comparison to ACC patients with no metastatic spread. Specifically, chromosome 6 and 12 and exclusively the entire chromosome 4 showed an increased frequency of chromosomal alterations with tumor progression. CONCLUSION Our data show a molecular evolution from primary tumors to local recurrences and distant metastases and pinpoint the critical chromosomal r
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