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The most regular treatment-related unpleasant events were diarrhea (36.2%) and hand-foot skin effect (34%), which were workable with conventional therapy. CONCLUSION LD-CCRT and sequential sorafenib treatment offered favorable OS and PFS with great tolerability. Tumor reduction using a short LD-CCRT allowed down-staging, subsequent curative therapy, and long-lasting survival in about 20% regarding the clients with advanced HCC. However, additional randomized tests are required to confirm these results. FACTOR B
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