https://www.selleckchem.com/pr....oducts/BafilomycinA1
BACKGROUND Total knee arthroplasty (TKA) is associated with moderate-to-severe postoperative pain. Satisfactory perioperative analgesia is essential for a good and predictable surgical outcome. Effective postoperative pain control is a major challenge to the treating surgeon and his team. Old age and multiple comorbidities restrict the choice of analgesics one can offer. Transdermal buprenorphine (TD, widely used in chronic pain management, has been rarely studied in acute postoperative setting. The purpose of this study was to
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