https://www.selleckchem.com/pr....oducts/telacebec-q20
OBJECTIVE Ankylosing spondylitis (AS) is a common spondyloarthropathy primarily affecting the axial skeleton and strongly associated with HLA-B*27 carriage. Genetic evidence implicates both autoinflammatory processes and autoimmunity against a HLA-B*27-restricted autoantigen in immunopathology. Additional to articular symptoms, up to 70% of AS patients present with concurrent bowel inflammation, suggesting that adverse interactions between a genetically-primed host immune system and the gut microbiome contributes to disease. Acco
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