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Meanwhile, patients with periodontitis might have a point of cognitive dysfunction, and SFRP1 and MIF may affect the periodontal tissue structure through Wnt/β-catenin sign pathway and take part in the incident and growth of intellectual dysfunction.Purpose to research the correlation between salivary anxiety markers chromogranin A (CgA), cortisol, α-amylase, β-endorphin and medical parameters of periodontitis, including sulcus bleeding index (SBI), periodontal probing depth (PD) and attachment reduction (AL). Metho

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