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The degradation of MNC in the NBo/PS system was achieved through electron transfer, while the degradation of MNC in the NBo/H2O2 system was mainly achieved through free radical addition. The degradation pathway mainly included deamidation reactions, C-C bond breakage and hydroxylation. Reusability of NBo showed that NBo was considerably stable in activating PS and H2O2 for degradation of MNC, which was cost-effective activator. This work provides a new perspective on the degradation mechanism of pollutants by Fe-Cu bimetallic sulfide acti