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In addition, F504L and N512Y substitutions may actually avoid bending associated with the β3-β4 loop that's needed is to contact the R1 band of ceftriaxone in the active site. Other mutations also appear to act by decreasing versatility into the necessary protein. Overall, our findings reveal that limitation of protein characteristics in PBP2 underpins the ESC opposition of N. gonorrhoeae. Posted under license by The American Society for Biochemistry and Molecular Biology, Inc.PURPOSE the typica
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