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Mechanistic studies indicate a number of nucleophilic 1,4 and 1,6 Michael inclusion reactions occur, followed by an aldol condensation effect, culminating into the development of three fused rings. The substances had been described as NMR studies plus the stereochemistry ended up being confirmed by X-ray analysis. The capacity to generate multigram amounts of these complex molecular scaffolds renders the method guaranteeing for medicinal chemistry campaigns. Herein, we additi
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