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Autonomic dysfunction affects the dynamic equilibrium and might cause individual gait differences. Further study is warranted to quantify the autonomic function and clarify individual variations in dynamic equilibrium, after unilateral CVS. This study aimed to investigate the effectiveness of topical allantoin application on wound healing in a rat chronic tympanic membrane perforation (TMP) model. A chronic TMP model was established with 25 healthy, female, 6-month-old, Sprague Dawley rats with chemical damage (trichloroacetic acid 50%