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64; 95%CI, 0.53-0.77; p0.0001). Grade 3+ complications and unintended intensive care admission occurred in 40 (9%) and 38 (9%) women, respectively, but were not associated with frailty (OR 1.21; 95%CI, 0.96-1.52; p=0.11). More-frail patients were more likely to delay postoperative chemotherapy (non-linear association p=0.009) and less likely to enroll in research (OR 0.84; 95%CI, 0.70-1.00; p=0.049). Greater frailty was associated with poorer overall survival (HR 1.16; 95%CI, 1.05-1.30; p=0.005). Frailty, as calculated by the MSK-FI,