https://www.selleckchem.com/products/Estrone.html
In utero and prepubertal development of the mammary glands occurs minimally in a hormone-independent manner until puberty where maturation of the hypothalamic-pituitary-gonadal axis drives an extensive remodelling. Nevertheless, because the immature glands contain functional hormone receptors, they are especially vulnerable to the effects of endocrine disruptors, such as brominated flame retardants (BFRs). BFRs are widespread chemicals added to household objects to reduce their flammability, and to which humans are ubiquitously exposed.
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