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Furthermore, the world of extracellular RNAs (exRNAs) is rapidly developing because exRNAs are a promising source of biomarkers in liquid biopsies, and because exRNAs seem to play key roles in intercellular and interspecies communication. Herein, we review current descriptions of tRNA-derived fragments within the extracellular area in all domain names of life, both in biofluids plus in cell culture. The goal of this a

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