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The primary study purpose of this research was to explore the bioactivity of Ti2448 alloy modified by sandblasted, large-grit, acid-etched (SLA), micro-arc oxidation (MAO) and anodic oxidation (AO), and to determine which regarding the three surface alterations is the better way for developing the osteogenesis of bone tissue marrow mesenchymal stem cells (BMMSCs). In vitro researches, the cytoskeleton, focal adhesion and expansion of BMMSCs indicated that both pure titanium and Ti2448

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