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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression Untreated ADHD can result in chronic underachievement and depression. This is especially the case when they fail to meet their professional and personal goals. The overlapping symptoms of the comorbidities of ADHD and depression can make it challenging to make a clear diagnosis. However, identifying the signs is the first step toward receiving treatment. 1. Feelings of Unworthiness Untreated ADHD

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