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0001) on serum SHBG concentrations compared with DNG and CMA (p less then 0.04 and p less then 0.002, respectively). Serum concentrations of total testosterone significantly decreased in all groups (p less then 0.0001). DRSP had a significantly greater effect on total testosterone concentrations compared with DNG (p = 0.002) and CMA (p less then 0.0001).Conclusion Our study showed that DNG exerted an important stimulatory effect on SHBG concentrations, which was less than that of DRSP but greater than that of CMA. Similar resul