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The investigation of the effect of carvone (a natural monoterpene) on liver damage caused by chronic immobilisation. Male Wistar rats were divided into four groups control, carvone, stress, and stress-carvone. To induce stress, rats were placed in a restrainer (6 h/21 day) and carvone was treated by gavage at a dose of 20 mg/kg. Alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase activities were significantly increased in sera of immobilised rats. Chronic immobilisation also increased malondialdehyde levels an
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