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Although sodium (Na) deficiency early in life impairs somatic development, its effect on neurocognitive features has not been extensively examined. We hypothesized that Na deficiency during very early life is enough to cause development failure and program neurobehavioral impairments in subsequent life. C57BL/6J mice were added to reduced- (0.4), normal- (1.5), or high- (3 g/kg) Na chow at weaning (PD22) and continued from the diet for 3 wk (to PD4. System composition and substance c

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